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Choose one answer

1. APlasma concentration rises linearly until the dose is stopped, with no tendency to plateau at a steady-state level
2. BPlasma concentration falls progressively despite continued dosing because of enzyme induction
3. CElimination becomes saturated once steady state is reached, causing accumulation to continue indefinitely
4. DA constant amount of drug is eliminated per unit time regardless of plasma concentration, as occurs with phenytoin or ethanol once metabolic enzymes are saturated
5. EA constant proportion of the remaining drug is eliminated per unit time, so concentration rises in decreasing increments towards a plateau